Cell Line Development
Our substantial experience in protein expression has lead to the development
and optimization of specific and original strains, culture media, tags and vectors,
which show particular interest according to several criteria such as productivity
of the process or GMP compliance. The following registered trademarks can be made available to PX’Therapeutics’ customers (without applying any license fees).
Pharm’Xpress : compliance with GMP Manufacturing
Pure’Xpress: high purity of protein for R&D
projects, Down Stream Process optimization for therapeutic projects
protein engineering for higher expression levels, Up Stream Process optimization
for therapeutic projects
InCell’Xpress : higher expression of insoluble proteins
in inclusion Bodies
We can propose high production and free-to-operate or proprietary expression
systems to our clients in order to select the most suitable system for the candidate
We offer bacterial (E. coli
) and mammalian (CHO, HEK, NSO, Insect
cells/baculovirus, etc.) systems.
With mammalian systems, we commonly propose
Transient Protein Expression to produce milligram quantities of a recombinant
protein for functional assays or animal studies.
We also offer Stable Cell Line
Development (monoclonal or pool) to address larger scale production at research
grade or set up high productivity cell line to be used for further GMP manufacturing